Download Bioaccumulation - New Aspects and Developments by B. Beek PDF

By B. Beek

The bioaccumulation of endocrine disruptors, chronic natural chemical compounds and different compounds of excessive environmental effect has develop into of accelerating curiosity in latest environmental study, probability research and toxicology. This quantity provides an up to date evaluate and introduces the reader to the hot proposal of "internal influence focus" linking bioaccumulation and biomagnification within the nutrients chain to ecotoxicology and probability review.

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J. Geyer et al. 2 Chemicals with Antiestrogenic Activity (Xenoantiestrogens) In contrast to substances which exert estrogen-like activity, a variety of nonsteroidal chemicals possess antiestrogenic activity. These chemicals are also named antiestrogens or xenoantiestrogens. The term antiestrogen can be applied to several classes of chemicals that modify, modulate, inhibit, or antagonize the actions and effects of natural estrogens. g. g. androgens and progestins). In this section we will refer only to antiestrogenic compounds of groups (a) and (b).

145e]. J. Geyer et al. h Chemical (common name, abbreviation, and/or IUPAC name) Molecular formula and molecular mass [g mol –1] RPP a (%) Water Solubility (mg l–1) log KOW Detected in water, sludge, sediment, algae, mussel, or fish. 10 effluents from wastewater treatment plants CAS no Chemical structure 1. Natural steroidal estrogens 17b-Estradiol (E2) 1,3,5(10)-Estratriene3,17b-diol Estriol (E3) 1,3,5(10)-Estratriene3,16a,17b-triol Estrone (E1) Bioaccumulation and Occurrence of Endocrine-Disrupting Chemicals (EDCs) Table 6.

38 Table 5. Concentrations of major estrogenic compounds in effluents of seven United Kingdom sewage treatment plants (STPs) Estrogenic compound Na Concentration [ng l–1] range 1. Natural and synthetic hormones 17b-Estradiol (E2) c Estrone (E1) c 17a-Ethinylestradiol c (EE2) 2. 08 Source: Adopted with modifications from Desbrow et al. [145b]. N; number of effluent samples. b The estrogen equivalent factors (EEFs) were established by the authors by using the RPP values from Table 6. c The hormones were present in effluents in a biologically-active unbound (free) form.

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